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Updated: May 21, 2025

Visualizing Shifts on Neuron-Glia Circuit with the Calcium Imaging Technique
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Published on: April 8, 2022

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GluA2を含むAMPA受容体は,Ca2+透過性チャネルの連続体を形成する

Federico Miguez-Cabello1, Xin-Tong Wang1,2, Yuhao Yan1,2

  • 1Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada.

Nature
|March 20, 2025
PubMed
まとめ

以前の考えに反して,GluA2を含むα-アミノ-3-ヒドロキシ-5-メチル-4-イソクサゾルプロピオン酸受容体 (AMPAR) は,カルシウム (Ca2+) を通過させる. 補助サブユニットは,このCa2+の透過性を動的に制御し,脳シグナル伝達と病気に影響を与えます.

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