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Updated: May 21, 2025

Author Spotlight: Developing Tools to Tune the Activity of Tyrosine Phosphatases
06:56

Author Spotlight: Developing Tools to Tune the Activity of Tyrosine Phosphatases

Published on: September 6, 2024

274

アゾベンゼンを運ぶDNAアプタマーアゴニストを用いた受容体チロシンキナーゼ活性とERKダイナミクスの可逆光学制御

Masahiro Wakano1, Masaya Tsunoda2, Keiji Murayama3

  • 1Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.

Journal of the American Chemical Society
|March 21, 2025
PubMed
まとめ

科学者たちは,受容体チロシンキナーゼ (RTK) の活性を正確に制御する光制御DNAアプタマーを開発しました. この新しいツールである Met-azo-aptamerは ERKのような細胞シグナル伝達経路を 光学的に制御し 細胞運命を研究しています

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