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Updated: May 20, 2025

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
12:09

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation

Published on: February 28, 2019

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STINGアゴニストベースのERターゲティング分子は,抗原のクロスプレゼンテーションを促進する

Xiafeng Wang1,2, Zhangping Huang2, Lixiao Xing3

  • 1Department of Laboratory Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Nature
|March 27, 2025
PubMed
まとめ

研究者らは,STINGアゴニストベースのERターゲティング分子 (SABER) を開発し,CD8+T細胞の反応を強化した. 腫瘍や感染症に対するワクチンの有効性を向上させる.

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Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo

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Purification of the Membrane Compartment for Endoplasmic Reticulum-associated Degradation of Exogenous Antigens in Cross-presentation12:48

Purification of the Membrane Compartment for Endoplasmic Reticulum-associated Degradation of Exogenous Antigens in Cross-presentation

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