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Updated: May 20, 2025

Single Synapse Indicators of Glutamate Release and Uptake in Acute Brain Slices from Normal and Huntington Mice
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生理学的温度でのAMPA亜型iGluRのグルタマートゲート

Anish Kumar Mondal1,2, Elisa Carrillo3, Vasanthi Jayaraman4,5

  • 1Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Nature
|March 27, 2025
PubMed
まとめ

研究者らは,イオノトロプ的グルタミン酸受容体 (iGluRs) のグルタミン酸ゲートのメカニズムを発見し,これらの重要なチャネルがどのように開閉されるかを明らかにしました. この発見は刺激性神経伝達と潜在的な治療目標の洞察を提供します.

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