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Updated: May 16, 2025

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
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P450ラジカルアリルミグラテースの誘導進化によって可能になった触媒的エナチオセレクティブ・スマイルの再編成

Wenzhen Fu1, Katherina Murcek2, Jasper Chen1

  • 1Department of Chemistry and Biochemistry, University of California Santa Barbara, Santa Barbara, California 93106, United States.

Journal of the American Chemical Society
|April 1, 2025
PubMed
まとめ

研究者らは,P450酵素を用いた最初の触媒的エナチオセレクティブ・スマイルズ再配置を開発した. この生物触媒法では,単純な前体から四次性ステレオセンターを持つ複雑な分子を効率的に生成します.

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