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Updated: May 21, 2025

In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression
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局所特有のレトロトランスポゾン活性を再プログラムして新しいDNA部位に

Christopher W Fell1,2,3,4, Lukas Villiger4, Justin Lim4

  • 1Department of Medicine, Division of Engineering in Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Nature
|April 9, 2025
PubMed
まとめ

研究者はSTITCHRという 新しいシステムを設計し 精密で傷跡のない ゲノム編集を実現しました このレトロエレメントベースのツールは,分裂する細胞と分裂しない細胞の両方で,標的の位置に遺伝物質を効率的に挿入することを可能にします.

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