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Updated: May 13, 2025

Paramagnetic Relaxation Enhancement for Detecting and Characterizing Self-Associations of Intrinsically Disordered Proteins
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Paramagnetic Relaxation Enhancement for Detecting and Characterizing Self-Associations of Intrinsically Disordered Proteins

Published on: September 23, 2021

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NMRスペクトロシーによるタンパク質の秩序と乱れを解読する

Lorenzo Bracaglia1, Silvia Oliveti1, Isabella C Felli1

  • 1Department of Chemistry "Ugo Schiff" and Magnetic Resonance Center, University of Florence, Sesto Fiorentino 50019, Italy.

Journal of the American Chemical Society
|April 14, 2025
PubMed
まとめ

CREB結合タンパク質 (CBP) のような複雑なタンパク質を研究するには,より大きな構造を調べる必要があります. 新しいNMR方法は,CBPにおける本質的に乱れた領域 (IDR) と球体領域の相互作用を明らかにし,より深い洞察を提供している.

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