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Updated: May 10, 2025

Residue-Specific Exchange of Proline by Proline Analogs in Fluorescent Proteins: How "Molecular Surgery" of the Backbone Affects Folding and Stability
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Residue-Specific Exchange of Proline by Proline Analogs in Fluorescent Proteins: How "Molecular Surgery" of the Backbone Affects Folding and Stability

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中間状態は,ストレート反応性合成ポリペプチドのケラチンのようなα-to-β変換を可能にする

Tianjian Yang1, Jianan Mao2, Tianrui Xue3

  • 1Polymer Program, Institute of Materials Science, University of Connecticut, Storrs, Connecticut 06269, United States.

Journal of the American Chemical Society
|April 22, 2025
PubMed
まとめ

合成ポリペプチドは自然の繊維状タンパク質を模倣し,高温でアルファヘリル構造からベータシート構造に移行します. これは高度な材料設計のための 強化された機械的性質を提供します.

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