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Updated: May 10, 2025

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
06:34

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS

Published on: June 20, 2014

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光触媒と化学選択のH/D交換でα-Thio C ((sp3) -Hボンド

Riku Ogasahara1, Miyu Mae1, Yuki Itabashi2

  • 1Graduate School of Pharmaceutical Sciences, The University of Osaka, 1-6 Yamada-oka, Suita, Osaka 565-0871, Japan.

Journal of the American Chemical Society
|April 24, 2025
PubMed
まとめ

この研究では,有機光触媒と重水 (D2O) を用いてチオC ((sp3) -H結合をデュテレーションするための高度な化学選択的方法が導入されています. この突破により 薬の発見とイメージングの用途に デウテリウムを正確に組み込むことが可能になりました

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