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Updated: May 22, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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(+) - ルブリフローラクトンAのイール触媒化,ステレオ選択的全合成

Jun-Jie Liu1,2, Zhi-Bin Ni1,2, Lei Li1

  • 1State Key Laboratory of Phytochemistry and Natural Medicines, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.

Journal of the American Chemical Society
|May 9, 2025
PubMed
まとめ

この研究では,複合的な天然製品である (+) - ルブリフローラクトンAの最初のステレオ制御された全合成が詳細に示されています. 主なステップは,ブテノリド環を形成するためのイリジウム触媒によるアリレーションと,複雑なABCDEF環システムの構築です.

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