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Updated: May 13, 2025

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
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An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis

Published on: September 12, 2019

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ニボルマブとイピリムマブとレンバチニブまたはソラフェニブを併用して,切除できない肝細胞癌の第一線治療 (CheckMate 9DW):オープンラベル,ランダム化,第3相試験

Thomas Yau1, Peter R Galle2, Thomas Decaens3

  • 1Centre of Cancer Medicine and University Department of Medicine, The University of Hong Kong, Hong Kong.

Lancet (London, England)
|May 11, 2025
PubMed
まとめ

ニボルマブとイピリムマブは,レンバチニブまたはソラフェニブと比較して,切除できない肝細胞癌患者の全生存期間を有意に改善しました. この組み合わせ治療は,管理可能な安全性プロファイルを持つ新しい第一線治療の選択肢を提供します.

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