Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

8.0K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
8.0K
Association Areas of the Cortex01:21

Association Areas of the Cortex

10.2K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
10.2K
Somatosensory, Motor, and Association Cortex01:23

Somatosensory, Motor, and Association Cortex

5.0K
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
5.0K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Cross-Modality Alignment of Spatial Transcriptomics, Multiplexed Imaging, and Histology with PHARAOH.

Research square·2026
Same author

A Retinoic Acid Autoregulatory Loop Governing Prefrontal-Motor Arealization.

bioRxiv : the preprint server for biology·2026
Same author

The MacBrain Resource Center (MBRC) rhesus macaque postnatal brain histology datasets: Enabling new discoveries through NHP tissue and digital data Repositories.

Journal of anatomy·2026
Same author

Comparative analysis of the cellular landscape in mammalian striatum.

Nature communications·2026
Same author

A critical initialization for biological neural networks.

Nature·2026
Same author

Spatial atlas of diabetic kidney disease reveals a B cell-rich subgroup.

Nature·2026
Same journal

Family of magnetic field-boosted superconductors in rhombohedral graphene.

Nature·2026
Same journal

What's the human cost of US research turmoil? A new film finds out.

Nature·2026
Same journal

Daily briefing: Ovaries start a second job after menopause.

Nature·2026
Same journal

Audio long read: Is the peptide craze backed by science? The promise behind the hype.

Nature·2026
Same journal

Scientists fight back against far-right plans to restrict academic freedom in Germany.

Nature·2026
Same journal

How AI can crack open the 'hidden curriculum' for neurodivergent students.

Nature·2026
関連記事をすべて見る

関連する実験動画

Updated: Apr 28, 2026

Multi-layer Cortical Ca2+ Imaging in Freely Moving Mice with Prism Probes and Miniaturized Fluorescence Microscopy
10:35

Multi-layer Cortical Ca2+ Imaging in Freely Moving Mice with Prism Probes and Miniaturized Fluorescence Microscopy

Published on: June 13, 2017

30.9K

空間トランスクリプトミックは,人間の皮質層と領域の仕様を示している.

Xuyu Qian1,2, Kyle Coleman3, Shunzhou Jiang3

  • 1Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. qianxuyu@gmail.com.

Nature
|May 14, 2025
PubMed
まとめ
この要約は機械生成です。

この研究は,空間単細胞解像度を用いてヒト胎児の脳の発達をマッピングし,皮質領域形成と初期層の確立の異なるモードを明らかにしています. 発見は脳の発達と 分子特異性における 空間的な文脈の重要性を強調しています

さらに関連する動画

Isolation and Cultivation of Neural Progenitors Followed by Chromatin-Immunoprecipitation of Histone 3 Lysine 79 Dimethylation Mark
10:09

Isolation and Cultivation of Neural Progenitors Followed by Chromatin-Immunoprecipitation of Histone 3 Lysine 79 Dimethylation Mark

Published on: January 26, 2018

7.4K
Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex
09:55

Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex

Published on: September 5, 2018

8.3K

関連する実験動画

Last Updated: Apr 28, 2026

Multi-layer Cortical Ca2+ Imaging in Freely Moving Mice with Prism Probes and Miniaturized Fluorescence Microscopy
10:35

Multi-layer Cortical Ca2+ Imaging in Freely Moving Mice with Prism Probes and Miniaturized Fluorescence Microscopy

Published on: June 13, 2017

30.9K
Isolation and Cultivation of Neural Progenitors Followed by Chromatin-Immunoprecipitation of Histone 3 Lysine 79 Dimethylation Mark
10:09

Isolation and Cultivation of Neural Progenitors Followed by Chromatin-Immunoprecipitation of Histone 3 Lysine 79 Dimethylation Mark

Published on: January 26, 2018

7.4K
Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex
09:55

Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex

Published on: September 5, 2018

8.3K

科学分野:

  • 神経科学
  • 発達生物学
  • ゲノミクス

背景:

  • 人間の脳皮質の発達には 分子や構造の異なる層や領域が含まれます
  • シングル・セル・トランスクリプトミクスは理解を深めたが,空間的な文脈をなくした.
  • 空間的解像度は 発達過程を理解するために不可欠です

研究 の 目的:

  • 空間的な単細胞解像度でヒト胎児皮質の分子,細胞,および細胞構造の発達を調査する.
  • 人間の皮質の発達に関する包括的な空間アトラスを作成する.
  • 皮質層と領域の仕様を解明する

主な方法:

  • 空間トランスクリプトミクスのための多重複合エラーロバスト光 in situ ハイブリデーション (MERFISH).
  • 細胞識別のための ディープラーニングベースの 核分割
  • 単核RNAの配列化による統合

主要な成果:

  • 8つの皮質領域と7つの時間点にわたる 1千8百万以上の細胞の空間アトラスを確立しました.
  • 6層の皮質構造の初期形成を特定した. 目に見える細胞構造の層よりも前に.
  • V1とV2の視野皮質の間の突然の境界を含む,皮質領域の特異性の連続的および離散的なモードを発見した.
  • 早期のシナプトゲネシスのアップレギュレーションがV1に特異的な4層ニューロンで示された.

結論:

  • 空間的関係は,皮質の層と領域の分子特異化にとって重要です.
  • この研究は,皮質領域化のグラデーションのみモデルに挑戦しています.
  • この研究は空間的に解明された脳のアトラスのパラダイムを確立しています