関連する実験動画

Updated: May 23, 2025

Monitoring GPCR-β-arrestin1/2 Interactions in Real Time Living Systems to Accelerate Drug Discovery
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Published on: June 28, 2019

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カモカイン受容体へのアストリン結合に対するリン酸化バーコードの作用

Qiuyan Chen1,2, Christopher T Schafer3,4, Somnath Mukherjee5

  • 1Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA. qch2@iu.edu.

Nature
|May 21, 2025
PubMed
まとめ

異なるGタンパク質結合受容体 (GPCR) キナーゼは,受容体において独特のリン酸化パターンを生み出します. これらのパターンはアストリン結合の仕方に影響し,細胞の結果と受容体の機能に影響します.

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