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Updated: Sep 19, 2025

Measurement of BK-polyomavirus Non-Coding Control Region Driven Transcriptional Activity Via Flow Cytometry
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Published on: July 13, 2019

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ウイルスのタンパク質によって引き起こされるセントロメリックDNA増幅は,核cGASを活性化します

Xavier Lahaye1, Patrick Tran Van1, Camellia Chakraborty2

  • 1Institut Curie, PSL University, INSERM U932, Immunity and Cancer, Paris, France.

Cell
|June 3, 2025
PubMed
まとめ

ヘルペスウイルスは,セントロメアを乱すことで核cGAS免疫を活性化し,DNA増幅につながります. このウイルスが誘発したセントロメリックDNA増幅および認識 (VICAR) 機構は,免疫活性化におけるセントロメアの新たな役割を明らかにしている.

キーワード:
CMV についてHSV-1 についてICP0 についてUL36USPVICAR についてcGAS についてセントロメア生まれつきの感覚トランスレションDNA合成

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