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Updated: Sep 19, 2025

Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
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Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions

Published on: July 30, 2017

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ネイティブアミドのパラジアム触媒メチレン β-C-H 化

Yi-Hao Li1, Jin-Quan Yu1

  • 1Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States.

Journal of the American Chemical Society
|June 5, 2025
PubMed
まとめ

研究者は,パラジウム触媒を用いたアミド内のC ((sp3) -H結合の選択的化のための新しい方法を開発した. この画期的な発見により,原生基質の直接メチレンC-H化が可能になり,有機合成と薬物の発見が進んでいます.

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