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Updated: Jun 13, 2025

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
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Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles

Published on: August 22, 2018

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1-アザビサイクロブタンのストレートリリース機能化によるエナンチオ制御アゼチジンライブラリ合成

Michael Bielecki1, Molhm Nassir1, Hayden A Sharma1

  • 1Department of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.

Journal of the American Chemical Society
|June 12, 2025
PubMed
まとめ

研究者たちは,複雑なステレオ純粋アゼチジンを合成するためのモジュラーメソッドを開発した. このアプローチは並列合成を可能にし,ヒトの癌細胞で高い選択性を持つ特定のタンパク質を特定するプローブを作成するために使用されました.

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