関連する実験動画

Updated: Jun 15, 2025

De novo Identification of Actively Translated Open Reading Frames with Ribosome Profiling Data
08:23

De novo Identification of Actively Translated Open Reading Frames with Ribosome Profiling Data

Published on: February 18, 2022

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大規模な並列リボソームプロファイルの使用による汎ウイルスORFの発見

Shira Weingarten-Gabbay1,2,3, Matthew R Bauer4, Alexandra C Stanton1,5,6

  • 1Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Science (New York, N.Y.)
|June 12, 2025
PubMed
まとめ

科学者は,大量並列リボソームプロファイリング (MPRP) を使用して,何千もの新しいウイルスオープンリーディングフレーム (ORF) を発見しました. これらの発見は,新しいウイルスペプチドと規制要素を明らかにし,ワクチン標的を拡大し,ウイルスメカニズムを理解します.

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