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Updated: Jun 14, 2025

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
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Modification and Functionalization of the Guanidine Group by Tailor-made Precursors

Published on: April 27, 2017

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アルギニン-N,N'-ビスプレニルトランスファーゼ:連続グアニジン-N-プレニル化における切り替え可能な触媒

Kei Fujita1, Yuito Yamada1, Tomo Taniguchi2

  • 1Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-ku, Sapporo 060-0812, Japan.

Journal of the American Chemical Society
|June 13, 2025
PubMed
まとめ

研究者はペプチドに2つの脂質群 (バイスプレニレーション) を加える新しい酵素であるDciFを特定しました. 彼らはまた,酵素が1つまたは2つの脂質群を追加して,新しいペプチド薬の改変を可能にするかどうかを制御する方法を示しました.

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