関連する実験動画

Updated: Sep 19, 2025

Isolation of Translating Ribosomes Containing Peptidyl-tRNAs for Functional and Structural Analyses
11:19

Isolation of Translating Ribosomes Containing Peptidyl-tRNAs for Functional and Structural Analyses

Published on: February 25, 2011

20.0K

リボソームにおける解放因子媒介ペプチジル-tRNAの水解のメカニズム

Elena V Aleksandrova1, Egor A Syroegin1, Ritwika S Basu2

  • 1Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL, USA.

Science (New York, N.Y.)
|June 19, 2025
PubMed
まとめ

ペプチド放出因子 (RF) は,ペプチドリル-tRNAの水解を触媒化することで,タンパク質合成を終了させます. 新しい構造は,RFがペプチジル-tRNAを水ではなく2'-OHを触媒として活性化することを明らかにしています.

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