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Updated: Sep 18, 2025

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コリナージックニューロンの活動が,マスカリンシグナル伝達により,拡散性ミドルライン・グリオマの成長を促進する

Richard Drexler1, Antonia Drinnenberg2, Avishai Gavish3

  • 1Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA.

Cell
|June 20, 2025
PubMed
まとめ

中脳コレリン神経は,拡散性ミッドライン・グリオマ (DMG) の成長とオリゴデンドロサイト前駆体細胞 (OPC) の増殖を促進する. この効果は回路に依存し,DMG細胞のM1/M3受容体に作用するアセチルコリンによって媒介される.

キーワード:
DMG についてLDT についてOPC についてPPN についてコリン神経細胞拡散性ミドルライン・グリオマグリオマ側背のテグメンタム核ニューロンニューロン・グリオマニューロンの活動オリゴデンドロサイトオリゴデンドロゲネシスペドゥンキュロポンチン核

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