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Updated: Sep 18, 2025

Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion
07:30

Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion

Published on: May 10, 2018

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2型糖尿病と肥満の治療のためのGRKバイアスのアドレナergicアゴニスト

Aikaterini Motso1, Benjamin Pelcman2, Anastasia Kalinovich2

  • 1Atrogi AB, Stockholm, Sweden; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden; Department of Physiology & Pharmacology, Section for Personalized Medicine and Drug Development, Karolinska Institutet, Stockholm, Sweden.

Cell
|June 24, 2025
PubMed
まとめ

GRK2を標的とする新しいGタンパク質結合受容体 (GPCR) アゴニストは,2型糖尿病のより安全な治療法を提供します. これらの新しい化合物は臨床前モデルで有望であり,現在の治療法に関連する副作用を潜在的に軽減します.

キーワード:
BRET についてGLP-1 についてGPCR についてグルジアベータ2アゴニスト偏ったアゴニズム糖尿病メタボリズム肥満骨格筋

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