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Updated: Sep 18, 2025

Visualization of SARS-CoV-2 using Immuno RNA-Fluorescence In Situ Hybridization
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Published on: December 23, 2020

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SARS-CoV-2のNiRANドメインによるGTP媒介RNAのキャピングのメカニズムは未解決のままである

Gabriel I Small1, Seth A Darst2, Elizabeth A Campbell3

  • 1Laboratory of Molecular Pathogenesis, the Rockefeller University, 1230 York Avenue, New York, NY 10065, USA; Laboratory of Molecular Biophysics, the Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.

Cell
|June 26, 2025
PubMed
まとめ

SARS-CoV-2のNiRANドメインはmRNAのキャピングを開始する. Cryo-EMデータ分析は,GTP媒介のキャピングメカニズムに関する以前の主張に異議を唱え,それが未解決のままであることを示唆しています.

キーワード:
NiRANドメインSARS-CoV-2についてコロナウイルスクリオ・エムdeRNAylation (deRNAylation) についてmRNAキャピングnsp12 についてnsp9 について

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