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Updated: Sep 17, 2025

Assay for Phosphorylation and Microtubule Binding Along with Localization of Tau Protein in Colorectal Cancer Cells
12:55

Assay for Phosphorylation and Microtubule Binding Along with Localization of Tau Protein in Colorectal Cancer Cells

Published on: October 10, 2017

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チャペロン媒介によるタウ相分離,動,および毒性の調節

Cecilia Mörman1,2, Axel Leppert3,4, Giusy Pizzirusso5,6

  • 1Department of Medicine Huddinge, Karolinska Institutet, Huddinge, 141 52 Huddinge, Sweden.

Journal of the American Chemical Society
|June 30, 2025
PubMed
まとめ

Bri2 BRICHOSドメインは,二次核形成を阻害し,凝縮物形成を調節することにより,タウタンパク質の結合と神経毒性を抑制する. これはタンパク質の誤折り症の 治療策となる可能性があります

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