関連する実験動画

Updated: Sep 17, 2025

Generation of Integration-free Human Induced Pluripotent Stem Cells Using Hair-derived Keratinocytes
08:36

Generation of Integration-free Human Induced Pluripotent Stem Cells Using Hair-derived Keratinocytes

Published on: August 20, 2015

11.7K

人体組織ネットワークのソマティック・モザイク主義

Tim H H Coorens1,2, Ji Won Oh3,4, Yujin Angelina Choi5

  • 1Broad Institute of MIT and Harvard, Cambridge, MA, USA. tcoorens@broadinstitute.org.

Nature
|July 3, 2025
PubMed
まとめ

この研究は,健康なヒト組織における体内の変異を分類し,そのパターンと結果を理解します. 新しい技術の開発により これらのDNA変異の検出が改善され 病気の研究に不可欠です

さらに関連する動画

Characterizing Mutational Load and Clonal Composition of Human Blood07:58

Characterizing Mutational Load and Clonal Composition of Human Blood

Published on: July 11, 2019

7.5K
Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches09:35

Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches

Published on: April 20, 2021

6.9K

関連する概念動画

Crossing Over01:34

Crossing Over

Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I, where each chromosome—replicated in S phase—is now composed of two sister chromatids (identical copies) joined centrally.
The homologous pairs of sister chromosomes—one from the maternal and one from the paternal genome—then begin to align alongside each other lengthwise, matching corresponding DNA positions in a process...
148.0K
Somatic to iPS Cell Reprogramming01:29

Somatic to iPS Cell Reprogramming

Reprogramming alters the gene expression in somatic cells, transforming them into induced pluripotent stem (iPS) cells over several generations. Scientists can reprogram cells by introducing genes for four transcription factors—Oct4, Sox2, Klf4, and c-Myc (OSKM) by viral or non-viral methods. These factors are also known as Yamanaka factors after Shinya Yamanaka, who first generated iPS cells using mouse skin cells. Yamanaka was awarded the Nobel Prize in Physiology or Medicine in 2012...
2.3K
Hybrid Zones02:29

Hybrid Zones

Hybrid zones are narrow regions where two closely related species interact, mate, and produce hybrids. Relative to either parent species, hybrids may possess distinct phenotypic or genetic differences that impact their survival and reproductive success. The genetic variances introduced by hybridization influence species diversity and speciation processes within the hybrid zone.
20.3K