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Updated: Sep 17, 2025

X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050
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X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050

Published on: May 13, 2020

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固体NMRによって明らかにされたロムボイド触媒型内膜タンパク質分解の適合選択メカニズム

Shuaifei Hu1, Juan Li1, Jin Zhang1

  • 1Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, Hefei National Research Center for Interdisciplinary Sciences at the Microscale, University of Science and Technology of China, 230027 Hefei, P. R. China.

Journal of the American Chemical Society
|July 3, 2025
PubMed
まとめ

この研究では,ロンボ型プロテアゼ基板PsTatAのN端がリピッド二重層に拡張された形状を採用し,以前の仮定に異議を唱える. 脂質の組成と膜の厚さは,基質の動態とタンパク質の相互作用に影響する.

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