Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Photochemical Electrocyclic Reactions: Stereochemistry01:26

Photochemical Electrocyclic Reactions: Stereochemistry

1.9K
The absorption of UV–visible light by conjugated systems causes the promotion of an electron from the ground state to the excited state. Consequently, photochemical electrocyclic reactions proceed via the excited-state HOMO rather than the ground-state HOMO. Since the ground- and excited-state HOMOs have different symmetries, the stereochemical outcome of electrocyclic reactions depends on the mode of activation; i.e., thermal or photochemical.
Selection Rules: Photochemical Activation
1.9K
Concentration and Rate Law03:03

Concentration and Rate Law

32.3K
The rate of a reaction is affected by the concentrations of reactants. Rate laws (differential rate laws) or rate equations are mathematical expressions describing the relationship between the rate of a chemical reaction and the concentration of its reactants.
For example, in a generic reaction aA + bB ⟶ products, where a and b are stoichiometric coefficients, the rate law can be written as:
32.3K
E2 Reaction: Kinetics and Mechanism02:45

E2 Reaction: Kinetics and Mechanism

10.7K
SN2 substitutions and E2 eliminations of alkyl halides proceed via a concerted pathway. While the nucleophile attacks the alpha carbon in SN2 reactions, it functions as a strong base and abstracts a beta hydrogen in the E2 mechanism. The rate-limiting transition state in E2 elimination reactions is characterized by partially broken carbon–hydrogen and carbon–halogen bonds and a partially formed pi bond between the alpha and beta carbons. The beta hydrogen and halide are eliminated...
10.7K
π Electron Effects on Chemical Shift: Overview01:27

π Electron Effects on Chemical Shift: Overview

1.1K
An applied magnetic field causes loosely bound π-electrons in organic molecules to circulate, producing a local or induced diamagnetic field over a large spatial volume. As the molecules tumble in solution, the field generated by π-electrons in spherical substituents results in a zero net field. However, the net field generated by π-electrons in non-spherical substituents is not zero. The effect of this induced field depends on the orientation of the molecule with respect to B0,...
1.1K
Temperature Dependence on Reaction Rate02:55

Temperature Dependence on Reaction Rate

83.7K
The Collision Theory
Atoms, molecules, or ions must collide before they can react with each other. Atoms must be close together to form chemical bonds. This premise is the basis for a theory that explains many observations regarding chemical kinetics, including factors affecting reaction rates.
The collision theory is based on the postulates that (i) the reaction rate is proportional to the rate of reactant collisions, (ii) the reacting species collide in an orientation allowing contact between...
83.7K
E1 Reaction: Kinetics and Mechanism02:46

E1 Reaction: Kinetics and Mechanism

15.8K
Here, in contrast to the E2 reaction mechanism, we delve into the aspects of the E1 reaction mechanism, which has two steps: rate-limiting loss of the leaving group and abstraction of the beta hydrogen by a weak base. Typically, the experimental proof for the E1 mechanism is via kinetic studies or isotope studies. While the former demonstrates the first-order kinetics—the dependence of the reaction solely on substrate concentration—the latter proves the abstraction of hydrogen only...
15.8K
  1. ホーム
  3. 相関反応座標運動は,多受容体構造における電子とエネルギー移転の非添加率強化を生成する.
  1. ホーム
  3. 相関反応座標運動は,多受容体構造における電子とエネルギー移転の非添加率強化を生成する.

関連する実験動画

Single-Molecule Förster Resonance Energy Transfer Methods for Real-Time Investigation of the Holliday Junction Resolution by GEN1
11:27

Single-Molecule Förster Resonance Energy Transfer Methods for Real-Time Investigation of the Holliday Junction Resolution by GEN1

Published on: September 18, 2019

9.6K

相関反応座標運動は,多受容体構造における電子とエネルギー移転の非添加率強化を生成する.

Hanggai Nuomin1, Feng-Feng Song2, Peng Zhang1

  • 1Department of Chemistry, Duke University, Durham, North Carolina 27708, United States.

Journal of the American Chemical Society
|July 16, 2025

PubMed で要約を見る

まとめ
この要約は機械生成です。

分子構造における量子干渉は,電子とエネルギー転送 (ETとEnT) の速度に大きな影響を及ぼします. 多受容体系では 添加的な効果ではなく 受容体と受容体の相互作用が 驚くほど高いET率を示しています

さらに関連する動画

Förster Resonance Energy Transfer Mapping: A New Methodology to Elucidate Global Structural Features
07:09

Förster Resonance Energy Transfer Mapping: A New Methodology to Elucidate Global Structural Features

Published on: March 16, 2022

2.6K
Using Three-color Single-molecule FRET to Study the Correlation of Protein Interactions
11:22

Using Three-color Single-molecule FRET to Study the Correlation of Protein Interactions

Published on: January 30, 2018

10.2K

関連する実験動画

Single-Molecule Förster Resonance Energy Transfer Methods for Real-Time Investigation of the Holliday Junction Resolution by GEN1
11:27

Single-Molecule Förster Resonance Energy Transfer Methods for Real-Time Investigation of the Holliday Junction Resolution by GEN1

Published on: September 18, 2019

9.6K
Förster Resonance Energy Transfer Mapping: A New Methodology to Elucidate Global Structural Features
07:09

Förster Resonance Energy Transfer Mapping: A New Methodology to Elucidate Global Structural Features

Published on: March 16, 2022

2.6K
Using Three-color Single-molecule FRET to Study the Correlation of Protein Interactions
11:22

Using Three-color Single-molecule FRET to Study the Correlation of Protein Interactions

Published on: January 30, 2018

10.2K

科学分野:

  • 物理化学
  • 量子化学について
  • 分子生物物理学

背景:

  • 多数のドナー,ブリッジ,または受容体を持つ分子構造は量子干渉を示すことができます.
  • 電子とエネルギーの伝達率 (ETとEnT) は,これらの量子効果によって影響を受けます.
  • 実験的な研究は,一つに対して2つの受容体を持つシステムでは,ET率の4〜5倍の増加を示しています.

研究 の 目的:

  • 多受容体の分子システムにおける結合相互作用を分析する.
  • 電子とエネルギーの移転の観測された速度の向上を,単純な添加モデルを超えて説明する.
  • 複雑な分子構造におけるETとEnTの運動を調整するための戦略を特定する.

主な方法:

  • 多受容体のシステムにおける結合相互作用の分析
  • ETとEnTの速度に対する量子干渉効果の理論的調査.
  • 反応の自由エネルギー,ドナー-受容器結合,および反応座標運動に影響を与える要因の検討.

主要な成果:

  • マルチアクセプターシステムでの速度向上は,単純な添加予測を超えています.
  • 受容体と受容体の相互作用は,これらの増加率の源として特定されています.
  • これらの相互作用は,反応の自由エネルギー,ドナー-受容体結合,および反応-座標のダイナミクスを修正する.

    • 結論:

    • 多受容体システムにおける驚くべき速度の向上は,受容体間の相互作用によって説明される.
    • これらの相互作用を理解することで,ETとEnTの割合を予測し制御することができます.
    • この研究は,電子とエネルギーの特性を合わせた分子システムを設計するための枠組みを提供します.