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Updated: Sep 15, 2025

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
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進行中のゲノム倍増は,卵巣がんにおける進化性と免疫を形作る

Andrew McPherson1,2, Ignacio Vázquez-García3,4,5,6,7, Matthew A Myers3,4

  • 1Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. mcphera1@mskcc.org.

Nature
|July 16, 2025
PubMed
まとめ

全ゲノム倍化 (WGD) は 卵巣腫瘍における癌の進化と免疫回避を促します この進行中のプロセスは腫瘍の多様性,染色体不安定性,免疫抑制に影響を与え,新しい治療標的を明らかにします.

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