Jove
Visualize
お問い合わせ

関連する概念動画

Microbial Nutrition01:28

Microbial Nutrition

304
Organisms exhibit remarkable metabolic diversity, categorized based on how they acquire energy and carbon. These strategies enable survival in various ecological niches and are essential for maintaining energy flow and nutrient cycling within ecosystems.Energy and Carbon SourcesOrganisms are classified as phototrophs or chemotrophs based on energy acquisition. Phototrophs use light as their energy source, while chemotrophs rely on oxidizing chemical compounds. Further differentiation arises...
304
Regulation of Food Intake01:30

Regulation of Food Intake

472
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
472
Microbial Growth Media01:27

Microbial Growth Media

256
Microbial growth media are essential tools in microbiology, providing the nutrients and conditions necessary to cultivate and study microorganisms. These media are categorized by their composition, consistency, and functional roles, enabling researchers to investigate microbial physiology, behavior, and interactions.Types and Consistencies of Growth MediaGrowth media can be solid, liquid, or semisolid. Solid media, often agar-based, allow visible colony growth for isolation and enumeration.
256
Methods for Controlling Microbial Growth01:29

Methods for Controlling Microbial Growth

496
Microbial growth control refers to various methods employed to inhibit, reduce, or eliminate microorganisms to ensure safety and hygiene across different settings. These methods are categorized based on the target environment and the level of microbial control required.Biocides are versatile agents designed to control microorganisms by either inhibiting their growth or outright killing them. These agents work through various physical, chemical, mechanical, or biological mechanisms. The...
496
Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

206
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
206
Stringent Response in E. coli01:23

Stringent Response in E. coli

53
Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
53

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

The Crunchometer, a low-cost, open-source acoustic analysis of feeding microstructure.

eLife·2026
Same author

Optogenetic insights into short- and long-duration random noise electrical stimulation.

Journal of neurophysiology·2026
Same author

In mice, a population of male germ cells show characteristics of non-apoptotic cell death during G0 arrest.

bioRxiv : the preprint server for biology·2026
Same author

CHARIOT-AAV: Conjugation of diverse vectors to adeno-associated viruses for delivery of large genes.

bioRxiv : the preprint server for biology·2026
Same author

The critical role of gut-brain signalling in eating behaviour and obesity.

Nature reviews. Gastroenterology & hepatology·2026
Same author

Targeted Magnetic Nanodiscs for Wireless Causal Manipulation of Gut-Brain Circuits.

bioRxiv : the preprint server for biology·2026
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する実験動画

Updated: Sep 14, 2025

Quantification of Macronutrients Intake in a Thermogenetic Neuronal Screen using Drosophila Larvae
07:24

Quantification of Macronutrients Intake in a Thermogenetic Neuronal Screen using Drosophila Larvae

Published on: June 11, 2020

3.8K

微生物のパターンに対する腸の感覚が 栄養を調節する

Winston W Liu1,2,3,4, Naama Reicher1,3, Emily Alway1,2,3

  • 1Laboratory of Gut Brain Neurobiology, Duke University, Durham, NC, USA.

Nature
|July 23, 2025
PubMed
まとめ

科学者は神経生物学的感覚と呼ばれる 新しい腸脳の感覚を発見しました この感覚はフラゲリンという 微生物の分子を用いて トール型受容体5 (TLR5) を介して脳に信号を送り 食事の行動を制御します

さらに関連する動画

A Bacterial Oral Feeding Assay with Antibiotic-Treated Mosquitoes
09:59

A Bacterial Oral Feeding Assay with Antibiotic-Treated Mosquitoes

Published on: September 12, 2020

6.5K
Rearing the Fruit Fly Drosophila melanogaster Under Axenic and Gnotobiotic Conditions
09:34

Rearing the Fruit Fly Drosophila melanogaster Under Axenic and Gnotobiotic Conditions

Published on: July 30, 2016

21.4K

関連する実験動画

Last Updated: Sep 14, 2025

Quantification of Macronutrients Intake in a Thermogenetic Neuronal Screen using Drosophila Larvae
07:24

Quantification of Macronutrients Intake in a Thermogenetic Neuronal Screen using Drosophila Larvae

Published on: June 11, 2020

3.8K
A Bacterial Oral Feeding Assay with Antibiotic-Treated Mosquitoes
09:59

A Bacterial Oral Feeding Assay with Antibiotic-Treated Mosquitoes

Published on: September 12, 2020

6.5K
Rearing the Fruit Fly Drosophila melanogaster Under Axenic and Gnotobiotic Conditions
09:34

Rearing the Fruit Fly Drosophila melanogaster Under Axenic and Gnotobiotic Conditions

Published on: July 30, 2016

21.4K

科学分野:

  • 神経科学
  • 微生物学
  • 胃腸内科

背景:

  • 宿主には 寄生した微生物を感知し 反応するメカニズムが必要です
  • 腸と脳のコミュニケーションは 宿主の行動や 食事の選択を制御します
  • 腸内微生物刺激に対するリアルタイムの感覚メカニズムは以前は知られていなかった.

研究 の 目的:

  • 腸内微生物の刺激に 反応する感覚的メカニズムの発見です
  • 腸内の微生物の感知に関与する 分子経路を特定する
  • この感覚が宿主の行動を 制御する役割を説明する.

主な方法:

  • ネズミの腸内ニューロポッド細胞に対するフラゲリンの効果を研究した.
  • トール型受容体5 (TLR5) ノックアウトモデルを使用した.
  • 試験されたペプチドYY (PYY) の放出とヴァガルノドーズのニューロン活性化.
  • フラゲリンに対する反応として 食事の行動と体重増加を評価した.

主要な成果:

  • フラゲリンは結腸神経足細胞のTLR5を刺激し,PYYの放出につながります.
  • このシグナル伝達経路は 食事の行動を制御し 食事の摂取量を減らします
  • ニューロポッド細胞にTLR5が欠けていたマウスは,食物摂取量と体重増加を示した.
  • フラゲリン誘発の栄養減少は,免疫反応や微生物群の存在とは無関係です.

結論:

  • 神経生物学的感覚という 新しい腸-脳感覚経路が 発見されました
  • この感覚は 宿主がフラゲリンのような 微生物の分子パターンに反応して 行動を調整することを可能にします
  • 神経生物学的感覚は 腸-脳神経回路を通じて活動し 神経足の細胞と ヴァーガルニューロンが関与しています