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Updated: Sep 13, 2025

Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source
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Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source

Published on: May 29, 2021

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フラグメントベースの薬物発見のための3次元フラグメントの作成のためのモジュラー合成プラットフォーム

Andres R Gomez-Angel1, Hanna F Klein1, Stephen Y Yao1

  • 1Department of Chemistry, University of York, York YO10 5DD, U.K.

Journal of the American Chemical Society
|July 30, 2025
PubMed
まとめ

新しいモジュラー・プラットフォームは,2Dの断片を新しいビルディングブロックを使用して鉛のような化合物に素早く3Dで処理できます. これは選択的なJAK3阻害剤を特定することで示された 薬剤発見を加速します

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