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Updated: Sep 11, 2025

Antibiotic Dereplication Using the Antibiotic Resistance Platform
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Antibiotic Dereplication Using the Antibiotic Resistance Platform

Published on: October 17, 2019

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新しい抗生物質の設計に用いるジェネラティブ・ディープラーニングのアプローチ

Aarti Krishnan1, Melis N Anahtar2, Jacqueline A Valeri3

  • 1Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Institute for Medical Engineering & Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.

Cell
|August 15, 2025
PubMed
まとめ

この研究は,新しい抗生物質を設計するための新しい AI フレームワークを導入します. 耐性菌に対する強力な抗菌作用を持つ化合物を 創り出し合成しました

キーワード:
ネイセリア・ゴノレアスタフィロコッカス・オーレウス抗生物質バクテリア感染de novo デザイン薬物の発見フラグメント人工知能グラフニューラルネットワーク機械学習

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