関連する実験動画

Updated: Sep 10, 2025

Comprehensive Analysis of Drug Response using the FLICK Assay
09:42

Comprehensive Analysis of Drug Response using the FLICK Assay

Published on: June 6, 2025

378

タゼメトスタットに関するFDA有害事象報告システムに関する現実世界の不均衡性分析

Qiong Liu1, Miaoqing Luo1, Mengge Gao1

  • 1Huadu District People's Hospital of Guangzhou, 48 Xinhua Road, Huadu District, Guangzhou, Guangdong, 510800, China.

Therapeutic innovation & regulatory science
|August 20, 2025
PubMed
まとめ

EZH2阻害剤であるタゼメトスタットの実用的な安全性データは,疲労や吐き気のような一般的な有害事象を明らかにしました. このFDA有害事象報告システム (FAERS) の分析では,味覚障害や眠気などの新しい安全性信号が特定されました.

キーワード:
有害事象不釣り合い分析FAERS について薬用警戒についてタゼメトスタット

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Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
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The hazard ratio (HR) is a widely used measure in clinical trials to compare the risk of events, such as death or disease recurrence, between two groups over time. It reflects the ratio of hazard rates—the instantaneous risk of the event occurring—between a treatment group and a control group. This measure provides valuable insights into the relative effectiveness of a treatment by assessing how the risk of an event differs between the two groups.
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