2回オーソトピック心臓移植を受けた患者のCorynebacterium striatumによる感染症性大動脈炎

Wei Xiang¹, Ling-Yun Kong¹, Peng Zou¹

¹Cardiovascular center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Litanglu 168, Tiantongyuan, Changping District, Beijing, 102218, China.

BMC infectious diseases

|August 20, 2025

まとめ

Corynebacterium striatumによって引き起こされる感染症性大動脈炎は心臓移植後に稀である. 迅速な診断と治療により感染と血栓がうまく解消されました

科学分野:

心臓病科
感染症
移植医学

背景:

心臓移植 (HTx) 患者における感染症性大動脈炎 (IA) は珍しい合併症である.
Corynebacterium striatum (C. ストライアタム) によって引き起こされるIAは例外的にまれです.
このレポートは,第2のオーソトピックHTxから8ヶ月後の患者で,C.ストライアトムによるIAの症例を詳細に説明しています.

研究の目的:

心臓移植を受けた患者の Corynebacterium striatum による感染性大動脈炎を報告する
この病気の診断と成功管理を強調すること

主な方法:

2度目の心臓移植を受けた若者の症例報告です
臨床的な症状には,再発する発熱,持続する細菌血症,貧血,外周動脈栓塞が含まれていた.
診断手段には,トランストラシック・エコーカルディオグラフィ (TTE) とトランスエゾファゲアル・エコーカルディオグラフィ (TEE) が含まれていた.

主要な成果:

TEEは昇動性大動脈のアナストモティック部位にイントラルミナル・マスを発見した
6週間のバンコマイシン治療にうまく対応した
34ヶ月の追跡調査では,再発した感染や栓塞は認められませんでした.

結論:

心臓移植を受けた細菌血症患者の昇動性アアストモティック部位の評価の重要性を強調する.
常規の心声検査では弁や心臓内臓の関わりがない場合でも IAを考慮することが重要だと強調する.

キーワード:

コリネバクテリア・ストライアタム心臓移植感染性大動脈炎植物

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