非標的代謝学を用いて植物,動物,人間の健康を結びつける

Anita Fleming¹, Fred D Provenza², Frédéric Leroy³

¹Department of Agriculture and Life Sciences, Lincoln University, Lincoln, Christchurch, New Zealand.

Journal of animal science

|August 20, 2025

まとめ

ビタミンEやEPAのような有益な化合物で牛肉を豊かにしますこれらの栄養素は人間に伝わり消費後に代謝プロフィールを変化させ飼料と消費者の健康を結びつけます

科学分野:

栄養学
メタボロミクス
動物科学

背景:

多様な草原からの代謝物は,放牧牛の肉の質と人間の健康に影響を与えます.
トロフィックレベルでのこれらの化合物の移転を理解することは極めて重要です.

研究の目的:

3つの異なる牧草地システムで完成したアングス牛の代謝プロフィールを比較する.
牛肉の消費後のヒトの血プロファイルに対する牧草由来代謝物の影響を評価する.

主な方法:

アングス牛は,多年生ライグラス/ホワイトクローバー (PRG),複合多種 (CMS),または隣接する単一栽培の牧草地 (AMS) で飼育された.
牛肉パティを分析し,ヒト参加者を対象とした二重盲検のランダム化臨床試験で,食後の血代謝値が評価されました.
ガンマトコフェロールとEPAを含む主要な代謝産物について,ハーベージ,牛肉,ヒトの血を分析した.

主要な成果:

AMS草は高濃度のガンマトコフェロールとEPAを示した.
これらの化合物の高濃度は,AMSの牧場で飼育された牛の肉 (P < 0. 05) で確認された.
また,食後3~5時間でガマトコフェロールとEPA濃度が上昇した (P < 0. 05).

結論:

牧草の飼料の組成は,放牧牛の代謝プロフィールに直接影響を与えます.
多様な牧場からの食物の化合物は牛肉に伝わり,その後人間の代謝反応に影響します.
この研究は,牧草の多様性,動物の栄養,人間の健康の結果との間の新しいリンクを確立しています.

キーワード:

牛牛牛牧草管理人間健康についてメタボローム

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