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Updated: Sep 10, 2025

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
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Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

Published on: January 26, 2024

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最小自由エネルギー活性化経路に沿った αIIbβ3インテグリン構造の予測

Siva Dasetty1, Robert E Coffman2, Tamara C Bidone3

  • 1Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois.

Biophysical journal
|August 20, 2025
PubMed
まとめ

インテグリン活性化には,細胞シグナル伝達に不可欠な形状の変化が含まれます. この研究は,この移行中のインテグリンサブユニット内の相関的な動きを明らかにし,薬剤設計の洞察を提供します.

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