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Updated: Sep 8, 2025

Assessing Autophagic Flux by Measuring LC3, p62, and LAMP1 Co-localization Using Multispectral Imaging Flow Cytometry
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Assessing Autophagic Flux by Measuring LC3, p62, and LAMP1 Co-localization Using Multispectral Imaging Flow Cytometry

Published on: July 21, 2017

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Unc-51 Like Kinase 3 (ULK3) は,多発性骨髄腫における自己死と細胞生存に不可欠である

Marilena Tauro1, Tao Li1, Praneeth R Sudalagunta2

  • 1Department of Tumor Microenvironment & Metastasis, H. Lee Moffitt Cancer Center and Research Institute; Tampa, FL, USA.

Research square
|August 20, 2025
PubMed
まとめ

重要なオートファジー遺伝子であるULK3をターゲットにすることで,多発性骨髄腫 (MM) に対する新しい戦略が提供されます. ULK3を阻害すると,腫瘍の負荷が減り,耐性MM患者の薬剤感受性が回復する.

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Quantitative Analysis of Autophagy using Advanced 3D Fluorescence Microscopy09:59

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