孤立した筋膜炎が全身性白血病を明らかにする: 希少な初期発現

Amit Kumar¹, Sandeep Garg^2,3, Praveen Bharti³

¹General Medicine, Maulana Azad Medical College, New Delhi, IND.

Cureus

|August 20, 2025

まとめ

組織性赤血球性狼 (SLE) は,めったに筋肉炎のみで,筋肉の弱さを引き起こします. 早期診断と治療は患者の改善に不可欠です

科学分野:

リウマトロジ
免疫学
神経学

背景:

システミック・ルプス・エリテマトーサス (SLE) は複雑な自己免疫疾患で,臨床的な表象は様々です.
筋肉骨の症状はSLEではよく見られるが,初期症状である孤立した筋炎はまれで,診断を遅らせる可能性がある.

研究の目的:

単一の自己免疫性筋炎を起因する SLE の症例を報告する.
炎症性ミオパシーの差分診断においてSLEを考慮する重要性を強調する.

主な方法:

19歳の女性の進行中の筋肉の弱さです
診断には,血清のクリーアチンキナーゼ,抗核抗体,電気ミオグラフィー,筋肉バイオプシーが含まれていた.
2019年EULAR/ACRのSLEの基準を満たす抗dsDNAと抗Sm抗体を自己免疫検査で確認した.

主要な成果:

クレアチンキナーゼが上昇し,抗核抗体が陽性であった.
筋肉の生検で自己免疫性筋炎が確認され,さらなる検査でSLE特異の抗体が検出されました.
主要な筋炎のSLEの診断が確立されました.

結論:

孤立した筋炎は,全身性白血球症 (SLE) の主要な症状である可能性があります.
早期に認識し,コルチコステロイドとヒドロキシクロロキンを用いた,狼に関連した筋炎の治療は,臨床的に有意な改善をもたらしました.
このケースは,SLEを炎症性筋症の微分診断に含める必要性を強調しています. 特に近接筋の弱さのある若い女性では.

キーワード:

自己免疫疾患症例報告炎症性ミオパシー筋肉バイオプシー骨髄炎全身性赤血性狼

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