ポリファーマシーにおける健康知識と薬剤の遵守:臨床実務のための体系的レビュー

Inês Jordão^1,2, Patrícia Paiva^2,1,3, Patrícia Dias²

¹Faculty of Medicine, University of Coimbra, Coimbra, PRT.

Cureus

|August 20, 2025

まとめ

健康に関する知識の欠如は薬の服用に重大な影響を及ぼし,特に多剤薬局の患者で処方誤差を増加させる. HLを改善する介入は,患者の成果を向上させ,医療費を削減することができます.

科学分野:

医療サービス研究
忍耐して忠節を保つ
薬剤管理

背景:

健康に関する知識 (HL) は,薬剤の遵守に不可欠ですが,ポリファーマシーではあまり研究されていません.
HLが薬物使用と服従に与える直接的な影響に関する研究は限られている.
既存のアデレンス研究では,HLを主要な変数として優先する事はめったにありません.

研究の目的:

健康に関する知識レベルと薬剤の服用の関係に関する現在の証拠をまとめます
医療に関する知識の不足が薬の使用や患者の健康状態に与える影響を特定する.
多剤薬剤師の患者の健康に関する知識への介入の有効性を評価する.

主な方法:

2019年から2024年の間に発表された16の研究をPRISMAで体系的にレビューした.
PubMed,Scopus,SciELOのデータベースを介して行った文献検索.
HL評価ツールとアデランス対策を用いた研究に重点を置く.

主要な成果:

健康に関する知識の低さ (LHL) は,非意図的な不服従の2. 6倍,処方箋の誤った解釈の68%の増加 (p < 0. 01) と関連している.
薬剤師主導の介入と視覚的補助器具は,アデレンスを最大52%改善し,投与誤差を減少させました.
LHLの患者は30日間の再入院を35%多く経験しました.

結論:

ポリファーマの管理にHLスクリーニングを統合することは不可欠です.
HLに敏感な介入は薬の誤差と医療費の削減に不可欠です
政策立案者は,脆弱な患者集団のためのHL改善戦略を優先すべきです.

キーワード:

臨床的介入健康に関する知識健康への影響医療費薬の順守患者教育ポリファーマシー

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