ドイツの診療所にある肺科医による,耐火性または原因不明の慢性咳の患者の横断評価
Peter Kardos1, Heinrich Worth2, Ulrich Koehler3
1Lungenzentrum Frankfurt, Frankfurt am Main, Germany.
Frontiers in medicine
|August 20, 2025
まとめ
不治性慢性咳 (RCC) と不治性慢性咳 (UCC) は,ドイツの人口のそれぞれ0.21%と0.64%に罹患しています. この研究は女性におけるより高い罹患率と,これらの疾患の診断の遅延を強調しています.
科学分野:
- 肺科
- エピデミオロジー
- 臨床医学
背景:
- 慢性咳 (CC) は一般的な臨床症状です.
- 耐久性慢性咳 (RCC) と不解明性慢性咳 (UCC) は,欧州のガイドラインで定義された異なる実体です.
- RCC/ UCCの流行は,ドイツの外科医肺科での流行は,以前は知られていなかった.
研究 の 目的:
- ドイツの肺科医が診察する成人患者におけるRCC/UCCの流行を調査する.
- RCC/UCCの患者の人口統計と一般的な治療法を特定する.
主な方法:
- 横断的な観察研究は,ドイツの肺病診療所16カ所で実施された.
- RCCまたはUCCと診断された成人患者は含まれており,喫煙者は除外された.
- 流行率はDGPのガイドラインに基づいて分析された.
主要な成果:
- スクリーンされた患者22,140人のうち,421人が適格で,226人がRCC/ UCCの基準を満たした.
- ドイツにおけるRCC/UCCの流行率はそれぞれ0. 21%と0. 64%であった.
- ほとんどの患者は女性 (71. 3%) であり,治療に抵抗する慢性咳 (TRCC) が最も一般的であり (77. 9%),しばしば喘息またはGERDに関連している. 診断の遅延は平均6. 4年でした.
結論:
- これは,ドイツの二次医療の外科医におけるRCC/UCCの罹患率を推定した最初の研究である.
- 女性の方が罹患率が高く,診断の遅延が顕著であった.
- 発見は,RCC/UCCの診断と治療戦略の改善の必要性を強調しています.
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