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Updated: Sep 8, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
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Published on: December 7, 2021

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GHIST 2024:第1回ゲノム歴史推論戦略大会

Travis J Struck1, Andrew H Vaughn2,3, Austin Daigle4,5

  • 1Department of Molecular and Cellular Biology, University of Arizona, Tucson, AZ, USA.

bioRxiv : the preprint server for biology
|August 20, 2025
PubMed
まとめ

ゲノム 歴史 推論 戦略 トーナメント (GHIST) は,集団遺伝的方法のベンチマークを行いました. サイト周波数スペクトルの方法はうまく実行されましたが,柔軟なモデルは複雑な進化史に適しています.

キーワード:
競争人口統計人口ゲノミクス

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In the same year as the discovery of the Sanger sequencing method, another group of scientists, Allan Maxam and Walter Gilbert, demonstrated their chemical-cleavage method for DNA sequencing. The Maxam-Gilbert method relies on using different chemicals that can cleave the DNA sequence at specific sites, the separation of resulting DNA fragments of variable size using electrophoresis, and deciphering the DNA sequence from the resulting gel bands.
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Horizontal gene transfer (HGT) is a process where genetic material moves between organisms within the same generation, unlike vertical gene transfer, which occurs from parent to offspring. HGT plays a crucial role in microbial evolution, adaptation, and survival, particularly in shared environments like the human gut.Mobile genetic elements such as plasmids, prophages, integrons, insertion sequences, and transposons facilitate this process. HGT occurs through three primary mechanisms:...
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