Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Bacterial Growth Curve01:28

Bacterial Growth Curve

331
The bacterial growth curve is a fundamental concept in microbiology that describes the dynamics of bacterial population growth in a closed system with controlled environmental conditions, such as temperature and nutrient availability. This curve is divided into four distinct phases: lag, log (exponential), stationary, and death phases, each reflecting a unique stage of bacterial adaptation and growth. During the lag phase, bacteria acclimate to their surroundings by synthesizing essential...
331
Cell Size01:22

Cell Size

117.4K
Cell sizes vary widely among and within organisms. Bacterial cells range between 1-10 micrometers (μm)and are considerably smaller than most eukaryotic cells. The smallest bacteria are 0.1 μm in diameter—about a thousand times smaller than eukaryotic cells, which typically range from 10-100 μm.
Surface Area
Cells can take in nutrients and water via diffusion through the plasma membrane itself or through specific channels in the membrane. The area of the membrane surrounding...
117.4K
Biosynthesis in Bacteria01:24

Biosynthesis in Bacteria

104
Biosynthesis in bacteria is a fundamental anabolic process that generates essential macromolecules, including proteins, nucleic acids, lipids, and polysaccharides. These macromolecules are critical for cellular growth, replication, and function. The process is tightly regulated and energetically linked to catabolic pathways to ensure optimal resource utilization.Biosynthetic pathways begin with precursor metabolites such as pyruvate, acetyl-CoA, and glucose-6-phosphate derived from glycolysis,...
104
Microbial Morphologies01:29

Microbial Morphologies

766
Bacterial and archaeal cells exhibit remarkable diversity in shape and structure, critical in their adaptability and functionality. Among bacteria, the most commonly observed shapes include cocci and bacilli. Cocci are spherical and may exist singly or in groupings such as pairs (diplococci), chains (streptococci), clusters (staphylococci), or tetrads. Bacilli, in contrast, are rod-shaped and can also occur as single cells, in pairs, or chains, depending on their environmental and genetic...
766
Stringent Response in E. coli01:23

Stringent Response in E. coli

50
Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
50
Other Glycolytic Pathways01:24

Other Glycolytic Pathways

211
The pentose phosphate pathway (PPP) operates in parallel with glycolysis, facilitating the metabolism of both pentoses and glucose. This pathway consists of two distinct phases: the oxidative and non-oxidative phases. While it does not directly generate ATP, the intermediates formed during the process can integrate into glycolysis, contributing to cellular energy metabolism when required.Oxidative Phase: NADPH ProductionThe oxidative phase of the pentose phosphate pathway is primarily...
211

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Learning Epithelial Elasticity via Local Tension Remodeling.

bioRxiv : the preprint server for biology·2025
Same author

Gene expression cycles drive non-exponential bacterial growth.

Physical review research·2025
Same author

Reinforcement learning for adaptive control of phenotypically heterogeneous bacterial populations.

bioRxiv : the preprint server for biology·2025
Same author

Physical traits of supercompetitors in cell competition.

Journal of the Royal Society, Interface·2025
Same author

Mechanistic basis for non-exponential bacterial growth.

bioRxiv : the preprint server for biology·2025
Same author

Catalytic growth in a shared enzyme pool ensures robust control of centrosome size.

eLife·2025
Same journal

A human-specific genetic modifier reconfigures large-scale cortical network dynamics underlying behavioral performance.

bioRxiv : the preprint server for biology·2026
Same journal

<i>Staphylococcus aureus</i> uses a eukaryotic-like uridyltransferase to make UDP-GlcNAc for cell wall synthesis.

bioRxiv : the preprint server for biology·2026
Same journal

Dynamic redistribution of eIF4F controls cap-dependent translation initiation.

bioRxiv : the preprint server for biology·2026
Same journal

When does additional information improve accuracy of RNA secondary structure prediction?

bioRxiv : the preprint server for biology·2026
Same journal

Normative brain-state trajectories reveal deviation from healthy aging in Alzheimer's disease.

bioRxiv : the preprint server for biology·2026
Same journal

Noradrenergic infraslow rhythm during sleep is the critical link between heart-rate dynamics and memory consolidation.

bioRxiv : the preprint server for biology·2026
関連記事をすべて見る

関連する実験動画

Updated: Sep 8, 2025

Monitoring Intraspecies Competition in a Bacterial Cell Population by Cocultivation of Fluorescently Labelled Strains
06:45

Monitoring Intraspecies Competition in a Bacterial Cell Population by Cocultivation of Fluorescently Labelled Strains

Published on: January 18, 2014

8.7K

細胞の幾何学が 細菌の代謝効率を制限する

Arianna Cylke1, Shiladitya Banerjee2

  • 1Department of Physics, Carnegie Mellon University, Pittsburgh, PA 15213, USA.

bioRxiv : the preprint server for biology
|August 20, 2025
PubMed
まとめ
この要約は機械生成です。

バクテリアの細胞のサイズと形は 成長の効率に不可欠です この研究は,オーバーフロー代謝の初期に最適な成長が起き,より大きな表面積と体積の比が効率を改善することを明らかにしています.

さらに関連する動画

Bacterial Cell Culture at the Single-cell Level Inside Giant Vesicles
07:33

Bacterial Cell Culture at the Single-cell Level Inside Giant Vesicles

Published on: April 30, 2019

7.1K
Multi-scale Analysis of Bacterial Growth Under Stress Treatments
12:08

Multi-scale Analysis of Bacterial Growth Under Stress Treatments

Published on: November 28, 2019

9.6K

関連する実験動画

Last Updated: Sep 8, 2025

Monitoring Intraspecies Competition in a Bacterial Cell Population by Cocultivation of Fluorescently Labelled Strains
06:45

Monitoring Intraspecies Competition in a Bacterial Cell Population by Cocultivation of Fluorescently Labelled Strains

Published on: January 18, 2014

8.7K
Bacterial Cell Culture at the Single-cell Level Inside Giant Vesicles
07:33

Bacterial Cell Culture at the Single-cell Level Inside Giant Vesicles

Published on: April 30, 2019

7.1K
Multi-scale Analysis of Bacterial Growth Under Stress Treatments
12:08

Multi-scale Analysis of Bacterial Growth Under Stress Treatments

Published on: November 28, 2019

9.6K

科学分野:

  • 微生物学
  • システム生物学
  • バイオ物理学

背景:

  • 細菌の代謝戦略は 細胞の物理的特性と密接に関連しています
  • 細胞のサイズと形が バイオマス生産効率にどのように影響するかについては 定量的な理解は限られている.

研究 の 目的:

  • 生理学,代謝,幾何学を統合した全細胞モデルを開発し,細菌の成長の制約を探求する.
  • 細胞形態と栄養素の利用可能性が成長効率に与える影響を調査する.

主な方法:

  • バクテリアの生理学的モデルを開発した.
  • 統合されたプロテオーム配分,代謝流,物理的な限界を持つ細胞幾何学 (表面積,拡散).
  • 細胞形態と栄養素の利用可能性のシミュレーション

主要な成果:

  • 細胞の成長効率は栄養素の可用性で単調ではなく,オーバーフロー代謝の開始時にピークに達します.
  • 表面と体積の高い比率は 細菌の成長効率を大幅に高めます
  • 幾何学的な制約により 持続可能な最大細胞サイズは 成長率に逆比例する.

結論:

  • 過剰な代謝は栄養の利用と成長率の最適なトレードオフを意味します.
  • 物理的な制約,特に細胞の幾何学は 細菌の代謝戦略を根本的に形作り 細胞の大きさを制限する.
  • この研究は,微生物の細胞サイズと成長率に関する観察された限界のメカニズム的説明を提供します.