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Updated: Sep 8, 2025

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ドーパミンD3受容体のGo/zバイアス結合プロファイル

Lucrezia Zanetti1, Luca Franchini1, Shirsha Saha1

  • 1Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, NY 14642.

bioRxiv : the preprint server for biology
|August 20, 2025
PubMed
まとめ

ドーパミンD3受容体 (D3R) は,他のドーパミン受容体とは異なり,Giタンパク質を活性化しません. 特定の分子相互作用によって誘発されるこの選択的信号は 神経生理学的反応と治療設計に影響します

キーワード:
D3R についてGタンパク質結合受容体 (GPCR)細胞ベースの測定ドーパミナージックシステム神経薬理学

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