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Updated: Sep 8, 2025

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
08:56

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Published on: November 30, 2022

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薬学的に重要なヘテロアロマティック・ボロナートの問題のあるスズキ・ミヤウラ反応を克服する方法としてのデスルフィナティブ・クロスカップリング

David C Blakemore1, Andre Shavnya1, Michael C Willis2

  • 1Medicine Design, Pfizer Inc., Groton, Connecticut 06340, United States.

ACS medicinal chemistry letters
|August 20, 2025
PubMed
まとめ

研究者らは新しい2アザアリル硫酸塩とスルフォンを効率的な核愛反応剤として開発した. これは,アザアロマティックスの直接的なアリレーションにおける課題を克服し,広範な医薬品の適用を見出します.

キーワード:
クロスカップリングデスルフィナティブヘテロサイクルパラレル合成ピリジンサルフィナートサルフォン

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Preparation and Reactions of Sulfides

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