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Updated: Sep 8, 2025

An In Vivo Method for Evaluating the Gut-Blood Barrier and Liver Metabolism of Microbiota Products
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Published on: October 20, 2018

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性ホルモンのアンドロゲンは,腸内微生物群-TMAO経路を通じて血圧を上昇させる

Ying Li1, Hong-Li Jiang2, Lei Chen2

  • 1Department of Critical Care Nephrology and Blood Purification, the First Affiliated Hospital and Department of Physiology and Pathophysiology, School of Basic Medical Sciences; Xi'an Jiaotong University, China (Y.L., H.-B.L.).

Hypertension (Dallas, Tex. : 1979)
|August 20, 2025
PubMed
まとめ

男性性ホルモンである二酸化テストステロン (DHT) は腸内微生物群を変化させ,トリメチラミンN酸化物 (TMAO) を増加させることで高血圧を誘発する. この腸内微生物群-TMAO経路をターゲットにすることで 男性の高血圧の治療の可能性が生まれます

キーワード:
TMAOディヒドロテストステロン腸-脳軸高血圧性別の違い

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