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Updated: Sep 10, 2025

Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer
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Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer

Published on: January 12, 2020

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卵巣がんにおけるKCTDファミリー遺伝子の腫瘍誘導および診断の役割に関するメカニズム的洞察: 統合されたシリコおよびインビトロ分析

Ling Zhang1, Chong Cheng2, Bin Tang1

  • 1Centre for Reproductive Medicine, Changde Hospital, Xiangya School of Medicine, Central South University (The First People's Hospital of Changde City), Changde, China.

Cancer medicine
|August 20, 2025
PubMed
まとめ

カリウムチャネルテトラメリゼーションドメインを含む (KCTD) 遺伝子は卵巣がん (OC) で変化した発現を示します. いくつかのKCTD遺伝子は腫瘍抑制剤として作用し,OCの診断および治療バイオマーカーとしての可能性を示している.

キーワード:
KCTD についてOC についてバイオマーカー診断するmiRNA (ミラーナ)トリートメント

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M-Cdk Drives Transition Into Mitosis

Checkpoints throughout the cell cycle serve as safeguards and gatekeepers, allowing the cell cycle to progress in favorable conditions and slow or halt it in problematic ones. This regulation is known as the cell cycle control system.
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M cyclin...
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In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
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