関連する実験動画

Updated: Jul 20, 2026

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography
10:24

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Published on: February 19, 2014

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HTRA1依存型タンパク質分解は,年齢に関連する網膜変性を引き起こし,冠状新血管化を悪化させる

Kenneth J Katschke1, Tom Truong2, Victoria Pham3

  • 1Department of Immunology, Genentech Inc., South San Francisco CA 94080, USA.

Disease models & mechanisms
|August 20, 2025
PubMed
まとめ

この研究では,目のHTRA1タンパク質が増加すると,光受容体に損傷を与えることで,年齢関連の黄斑変性 (AMD) に寄与することが明らかになりました. この発見は,AMDの病原性および潜在的な治療目標の重要な要因を特定しています.

キーワード:
年齢による黄斑変性コロイド新血管化HTRA1 についてRBP3 について網膜の変性

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