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Updated: Sep 10, 2025

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
07:15

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

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冠動脈疾患における潜在的昼夜リズム関連の病原性遺伝子:メンデルのランダム化研究

Hongliang Zhang1, Zhenyan Zhao1, Wence Shi1

  • 1Coronary Heart Disease Center, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovascular Diseases, Beilishi Road 167, Xicheng District, Beijing 100037, China.

Postgraduate medical journal
|August 20, 2025
PubMed
まとめ

循環器リズム遺伝子RASD1とSREBF1は,冠動脈疾患 (CAD) の病原性に関連しています. このメンデルのランダム化研究は,CADの予防と治療のための治療目標としての彼らの可能性を強調しています.

キーワード:
メンデルのランダム化昼夜リズムコロカライゼーション冠動脈疾患マルチオミクス

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