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Updated: Sep 10, 2025

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice

Published on: June 12, 2021

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カレティキュリンの混乱は,CD8+ T細胞媒介の抗腫瘍免疫を強化する

Kaiyang Tang1, Lijian Wu1, Yuanzhi Hu1

  • 1School of Basic Medical Sciences, State Key Laboratory of Molecular Oncology, Tsinghua University , Beijing, China.

The Journal of experimental medicine
|August 20, 2025
PubMed
まとめ

カルレチクリン (CALR) とペプチド負荷複合体 (PLC) の成分を非活性化すると,予期せぬ形で腫瘍に対するCD8+ T細胞の反応が強化されます. この発見は癌の免疫療法の有効性を高める 新しい戦略を提示しています

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