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Updated: Sep 10, 2025

Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice
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TXN1をターゲットにすることで,P38 MAPK経路を通じてグリオマ細胞のG2M相停止とアポトーシスを誘導する

Lu Zhou1, Hongsheng Liang2, Chenyi Nie1

  • 1Northeast Agricultural University, Harbin, 150000, China.

Applied biochemistry and biotechnology
|August 20, 2025
PubMed
まとめ

膠原腫細胞におけるTXN1の抑制はASK1/ P38 MAPK経路を活性化し,細胞サイクル停止とアポトーシスを引き起こします. この発見は,膠原腫患者の予後を改善するための潜在的な治療戦略を提供します.

キーワード:
アポトーシスG2/M についてグリオマP38 MAPK についてTXN1 について

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