関連する実験動画

Updated: Sep 10, 2025

A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1
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A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1

Published on: March 18, 2017

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G-クアドルプレックス分解のDEAHボックスヘリケーズDHX36の二重DNAとRNA特異性の構造的基礎

Michael T Banco1, Tapas Paul2, Jiansen Jiang1

  • 1Biochemistry and Biophysics Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Cell reports
|August 20, 2025
PubMed
まとめ

DEAHボックスヘリケーズ36 (DHX36) 酵素は,DNAとRNAのG四重複体を分解することができる. 構造と運動の研究は,特定のドメインとループによってDHX36がDNAとRNA基板を区別することを明らかにしています.

キーワード:
アトピーゼCP: 分子生物学冷凍サンプル電子顕微鏡単一分子スーパーファミリー 2テトラッドテトラプレックス

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