関連する実験動画

Updated: Sep 10, 2025

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
11:44

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

Published on: January 24, 2016

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IRF7の交互に配合された同型は,ウイルス感染に対する反応を調整するために,インターフェロン発現を差異的に調節する

Asmita Panthi1, Max B Ferretti2, Olivia Howard2

  • 1Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Pharmacology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Cell reports
|August 20, 2025
PubMed
まとめ

インターフェロン調節因子7 (IRF7) の代替スプライシングにより,新しいタンパク質が生成されます. このexIRF7は,標準のcIRF7よりも効果的にウイルスに対する免疫反応を強化し,先天的な免疫力を改善します.

キーワード:
CELF2 についてCP: 免疫学IRF7 について代替スプライシング生まれつきの免疫インターフェロンイントロン保持タンパク質二重化トランスクリプションの活性化

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